The ability to metabolize and break down alcohol within your body is said to be due to genetics. Then what is the science behind the red face?

Alcohol is first broken down into a toxic metabolite called acetaldehyde by an enzyme called ADH. The more you have ADH enzymes, the easier for you to be hungover from a night out due to faster metabolism of alcohol.

Acetaldehyde is then metabolized into acetic acid by another enzyme called ALDH. People who naturally have more ALDH enzymes are better at breaking down the toxic metabolite into a non-toxic product. So they are less likely to become drunk and hungover.

Your genes determine the quantity of ADH and ALDH enzymes produced in your body.

ALDH2 gene is one of the factors that determine the amount of enzymes necessary for alcohol metabolism. If this gene is inactivated, then it is more likely for you to be hunger longer than others.

Studies have suggested that mutation in genes associated with alcohol metabolism is linked to the development of cancer. This is because cellular DNA can be damaged by acetaldehyde produced from alcohol metabolism.

Drinking alcohol during a night out can help you relieve some stress. But drink responsibly by considering your geneti tendency and your general health condition.


Genoplan provides genetic testing results on your physical tendency to metabolize alcohol and resulting alcohol flush reaction.